1-Benzylpiperidine-4-carbaldehyde

CAS Number22065-85-6
EC Number244-757-7
Molecular FormulaC13H17NO
Molecular Weight203.28
SMILESC1CN(CCC1C=O)CC2=CC=CC=C2
InChIKeySGIBOXBBPQRZDM-UHFFFAOYSA-N
MDLMFCD02258902
AppearanceColorless to pale yellow liquid

An N-benzyl protected piperidine-4-carbaldehyde. Widely used as a key intermediate in the synthesis of donepezil (an Alzheimer's drug) and other piperidine-containing pharmaceuticals. The aldehyde group enables reductive amination, condensation, and other C-C bond forming reactions.

Pharmaceutical intermediate; donepezil synthesis; piperidine building block

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