Catalog / (2R,4R)-4-甲基-2-哌啶甲酸乙酯 Ethyl (2R,4R)-4-methyl-2-piperidinecarboxylate

(2R,4R)-4-甲基-2-哌啶甲酸乙酯 Ethyl (2R,4R)-4-methyl-2-piperidinecarboxylate

Ethyl (2R,4R)-4-methylpiperidine-2-carboxylate

杂环手性化合物医药中间体哌啶阿加曲班中间体酯类

Molecular Structure

CAS Number

74892-82-3

Molecular Formula

C9H17NO2

Molecular Weight

171.24

Purity

97%

InChIKey

GHBNOCBWSUHAAA-HTQZYQBOSA-N

MDL Number

MFCD03093749

SMILES

CCOC(=O)C1CC(CCN1)C

Appearance

无色至浅黄色液体

Boiling Point

90-95°C/15 mmHg (predicted)

Density

0.975 g/cm³ (predicted)

Solubility

溶于乙醇、乙酸乙酯、THF等有机溶剂

Storage

2-8°C, 充氮保存

Description

(2R,4R)-4-甲基-2-哌啶甲酸乙酯是手性哌啶甲酸乙酯衍生物，作为阿加曲班 (Argatroban) 合成的重要手性中间体。由对应的哌啶甲酸与乙醇酯化制得，保留了手性中心的反式构型。

Applications

医药中间体; 阿加曲班合成; 手性砌块

Safety & Hazards

Classification: 刺激性 (GHS07)

H-statements: H315, H319, H335

P-statements: P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, P501

Ordering

Packaging: 100mg; 500mg; 1g; 5g; 25g

Status Check Availability

Purity 97%

Grade 实验级

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