Catalog / (2R,4R)-4-甲基-2-哌啶甲酸 (2R,4R)-4-Methylpiperidine-2-carboxylic acid

(2R,4R)-4-甲基-2-哌啶甲酸 (2R,4R)-4-Methylpiperidine-2-carboxylic acid

(2R,4R)-4-methylpiperidine-2-carboxylic acid

杂环手性化合物医药中间体羧酸哌啶阿加曲班中间体

Molecular Structure

CAS Number

74892-81-2

Molecular Formula

C7H13NO2

Molecular Weight

143.18

Purity

97%

InChIKey

UQHCHLWYGMSPJC-PHDIDXHHSA-N

MDL Number

MFCD03839858

SMILES

CC1CCNC(C1)C(=O)O

Appearance

白色至类白色固体

Melting Point

220-225°C (分解)

Solubility

溶于水（盐酸盐形式），微溶于乙醇

Storage

室温, 密封, 干燥保存

Description

(2R,4R)-4-甲基-2-哌啶甲酸是手性哌啶甲酸衍生物，作为阿加曲班 (Argatroban) 合成的关键手性砌块。具有手性中心的反式-4-甲基-2-羧基取代，是药物合成中重要的手性中间体。

Applications

医药中间体; 阿加曲班合成; 手性砌块

Safety & Hazards

Classification: 刺激性 (GHS07)

H-statements: H315, H319, H335

P-statements: P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, P501

Ordering

Packaging: 100mg; 500mg; 1g; 5g

Status Check Availability

Purity 97%

Grade 实验级

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