Catalog / 3-甲基-8-喹啉磺酰氯 3-Methyl-8-quinolinesulphonyl chloride

3-甲基-8-喹啉磺酰氯 3-Methyl-8-quinolinesulphonyl chloride

3-methylquinoline-8-sulfonyl chloride

杂环医药中间体喹啉磺酰氯阿加曲班中间体

Molecular Structure

CAS Number

74863-82-4

Molecular Formula

C10H8ClNO2S

Molecular Weight

241.69

Purity

97%

InChIKey

XCMAYGDQKTWICK-UHFFFAOYSA-N

MDL Number

MFCD02683367

SMILES

CC1=CC2=C(C(=CC=C2)S(=O)(=O)Cl)N=C1

Appearance

浅黄色至棕色结晶粉末

Melting Point

85-90°C

Solubility

溶于二氯甲烷、THF等有机溶剂，遇水分解

Storage

2-8°C, 干燥, 充氮, 防潮保存

Description

3-甲基-8-喹啉磺酰氯是阿加曲班 (Argatroban) 合成的关键中间体。分子中的磺酰氯基团具有高反应活性，可与胺类反应生成磺酰胺键。对水分敏感，需在无水条件下操作。

Applications

医药中间体; 阿加曲班合成; 磺酰胺试剂

Safety & Hazards

Classification: 腐蚀性 (GHS05); 刺激性 (GHS07)

H-statements: H302, H314, H335

P-statements: P260, P261, P264, P270, P271, P280, P301+P312, P301+P330+P331, P303+P361+P353, P304+P340, P305+P351+P338, P310, P321, P330, P363, P405, P501

Ordering

Packaging: 1g; 5g; 25g; 100g

Availability

Status Check Availability

Purity 97%

Grade 实验级

Request Quote