Catalog / 8-(2-羟基苯甲酰胺基)辛酸钠

8-(2-羟基苯甲酰胺基)辛酸钠

Salcaprozate sodium

苯环酰胺羧酸盐药物递送药用辅料

Molecular Structure

CAS Number

203787-91-1

Molecular Formula

C15H20NNaO4

Molecular Weight

301.32

Purity

98%

InChIKey

UOENJXXSKABLJL-UHFFFAOYSA-M

MDL Number

MFCD00952954

SMILES

C1=CC=C(C(=C1)C(=O)NCCCCCCCC(=O)[O-])O.[Na+]

Appearance

白色至类白色粉末

Melting Point

198-202°C (分解)

Solubility

易溶于水，溶于甲醇、DMSO

Storage

室温, 密封, 干燥保存

Description

Salcaprozate sodium (SNAC) 是一种肠道渗透增强剂，作为药物递送促进剂用于大分子口服制剂。是诺和泰口服制剂 (Rybelsus, 口服索马鲁肽) 的关键辅料，已获得 FDA GRAS 认证。通过暂时改变胃上皮细胞膜通透性促进多肽类药物的口服吸收。

Applications

药物递送系统; 口服多肽制剂辅料; 渗透增强剂; 医药 API 中间体

Safety & Hazards

Classification: 刺激性 (GHS07)

H-statements: H315, H319, H335

P-statements: P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, P501

Ordering

Packaging: 1g; 5g; 25g; 100g; 1kg

Status Check Availability

Purity 98%

Grade 药用级 (GMP)

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